| Issum to Navodari | 1,135.86 mi (1,827.99 km) |
| Issum to Negresti-Oas | 798.68 mi (1,285.36 km) |
| Issum to Nehoiu | 1,002.19 mi (1,612.86 km) |
| Issum to Ocna Mures | 864.47 mi (1,391.24 km) |
| Issum to Odobesti | 1,018.72 mi (1,639.47 km) |
| Issum to Odorheiu Secuiesc | 926.54 mi (1,491.11 km) |
| Issum to Oltenita | 1,064.88 mi (1,713.75 km) |
| Issum to Onesti | 989.45 mi (1,592.37 km) |
| Issum to Oradea | 761.40 mi (1,225.35 km) |
| Issum to Orastie | 857.43 mi (1,379.90 km) |
| Issum to Oravita | 830.50 mi (1,336.56 km) |
| Issum to Orsova | 871.30 mi (1,402.22 km) |
| Issum to Otelu Rosu | 836.65 mi (1,346.46 km) |
| Issum to Otopeni | 1,023.47 mi (1,647.11 km) |
| Issum to Ovidiu | 1,135.65 mi (1,827.65 km) |
