| Issum to El Ejido | 1,115.58 mi (1,795.36 km) |
| Issum to El Escorial | 908.45 mi (1,462.01 km) |
| Issum to El Espinar | 903.52 mi (1,454.07 km) |
| Issum to El Molar | 885.23 mi (1,424.64 km) |
| Issum to El Prat de Llobregat | 734.88 mi (1,182.68 km) |
| Issum to El Puerto de Santa Maria | 1,204.10 mi (1,937.80 km) |
| Issum to El Viso del Alcor | 1,143.35 mi (1,840.04 km) |
| Issum to Elche | 979.86 mi (1,576.94 km) |
| Issum to Elda | 967.68 mi (1,557.33 km) |
| Issum to Elgoibar | 707.37 mi (1,138.40 km) |
| Issum to Erandio | 717.56 mi (1,154.81 km) |
| Issum to Ermua | 711.20 mi (1,144.57 km) |
| Issum to Esparraguera | 723.73 mi (1,164.73 km) |
| Issum to Espartinas | 1,153.55 mi (1,856.46 km) |
| Issum to Esplugas de Llobregat | 731.53 mi (1,177.28 km) |
