| Issum to Olivenza | 1,102.34 mi (1,774.05 km) |
| Issum to Olot | 672.42 mi (1,082.16 km) |
| Issum to Onate | 717.93 mi (1,155.40 km) |
| Issum to Onda | 861.50 mi (1,386.45 km) |
| Issum to Onteniente | 941.93 mi (1,515.89 km) |
| Issum to Orihuela | 996.03 mi (1,602.96 km) |
| Issum to Osuna | 1,137.39 mi (1,830.46 km) |
| Issum to Ourense | 923.56 mi (1,486.33 km) |
| Issum to Oviedo | 802.94 mi (1,292.21 km) |
| Issum to Paiporta | 899.07 mi (1,446.92 km) |
| Issum to Pajara | 1,921.75 mi (3,092.76 km) |
| Issum to Palafolls | 703.63 mi (1,132.38 km) |
| Issum to Palafrugell | 682.30 mi (1,098.05 km) |
| Issum to Palamos | 687.50 mi (1,106.43 km) |
| Issum to Palencia | 835.76 mi (1,345.02 km) |
