| Issum to Serik | 1,571.88 mi (2,529.70 km) |
| Issum to Serinhisar | 1,470.47 mi (2,366.50 km) |
| Issum to Serinyol | 1,794.41 mi (2,887.82 km) |
| Issum to Seydisehir | 1,574.61 mi (2,534.10 km) |
| Issum to Seyhan | 1,730.31 mi (2,784.67 km) |
| Issum to Seyitgazi | 1,431.22 mi (2,303.32 km) |
| Issum to Siirt | 1,954.37 mi (3,145.26 km) |
| Issum to Sile | 1,308.53 mi (2,105.88 km) |
| Issum to Silifke | 1,706.03 mi (2,745.59 km) |
| Issum to Silivri | 1,260.19 mi (2,028.09 km) |
| Issum to Silopi | 2,006.62 mi (3,229.34 km) |
| Issum to Simav | 1,383.87 mi (2,227.12 km) |
| Issum to Sinanpasa | 1,447.97 mi (2,330.28 km) |
| Issum to Sindirgi | 1,346.02 mi (2,166.21 km) |
| Issum to Sinop | 1,496.65 mi (2,408.63 km) |
