| Issum to Eau Claire (Wisconsin) | 4,185.88 mi (6,736.53 km) |
| Issum to Echelon (New Jersey) | 3,803.02 mi (6,120.37 km) |
| Issum to Eden (North Carolina) | 4,149.09 mi (6,677.32 km) |
| Issum to Eden Prairie (Minnesota) | 4,252.04 mi (6,843.00 km) |
| Issum to Edgewater (Florida) | 4,571.31 mi (7,356.81 km) |
| Issum to Edgewater (New Jersey) | 3,718.20 mi (5,983.86 km) |
| Issum to Edgewood (Maryland) | 3,874.43 mi (6,235.30 km) |
| Issum to Edgewood (Washington) | 4,967.68 mi (7,994.71 km) |
| Issum to Edina (Minnesota) | 4,246.54 mi (6,834.15 km) |
| Issum to Edinburg (Texas) | 5,393.75 mi (8,680.41 km) |
| Issum to Edmond (Oklahoma) | 4,863.06 mi (7,826.34 km) |
| Issum to Edmonds (Washington) | 4,934.87 mi (7,941.91 km) |
| Issum to Edwards (Colorado) | 4,963.01 mi (7,987.20 km) |
| Issum to Edwardsville (Illinois) | 4,430.49 mi (7,130.19 km) |
| Issum to Effingham (Illinois) | 4,360.77 mi (7,017.98 km) |
