| Issum to Santa Rosa (California) | 5,504.15 mi (8,858.08 km) |
| Issum to Santaquin (Utah) | 5,104.67 mi (8,215.17 km) |
| Issum to Santee (California) | 5,673.85 mi (9,131.18 km) |
| Issum to Sapulpa (Oklahoma) | 4,797.57 mi (7,720.95 km) |
| Issum to Saraland (Alabama) | 4,763.11 mi (7,665.49 km) |
| Issum to Sarasota (Florida) | 4,719.83 mi (7,595.83 km) |
| Issum to Sarasota Springs (Florida) | 4,718.55 mi (7,593.77 km) |
| Issum to Saratoga (California) | 5,556.70 mi (8,942.64 km) |
| Issum to Saratoga Springs (New York) | 3,611.05 mi (5,811.43 km) |
| Issum to Saratoga Springs (Utah) | 5,087.09 mi (8,186.88 km) |
| Issum to Sartell (Minnesota) | 4,239.68 mi (6,823.11 km) |
| Issum to Satellite Beach (Florida) | 4,597.03 mi (7,398.21 km) |
| Issum to Sauk Rapids (Minnesota) | 4,238.46 mi (6,821.14 km) |
| Issum to Sault Ste. Marie (Michigan) | 3,856.43 mi (6,206.33 km) |
| Issum to Savage (Minnesota) | 4,253.42 mi (6,845.22 km) |
