| Issum to Storm Lake (Iowa) | 4,422.30 mi (7,117.00 km) |
| Issum to Storrs (Connecticut) | 3,606.00 mi (5,803.29 km) |
| Issum to Stoughton (Wisconsin) | 4,198.18 mi (6,756.32 km) |
| Issum to Stow (Ohio) | 3,992.87 mi (6,425.91 km) |
| Issum to Streamwood (Illinois) | 4,204.35 mi (6,766.25 km) |
| Issum to Streator (Illinois) | 4,271.99 mi (6,875.11 km) |
| Issum to Streetsboro (Ohio) | 3,986.52 mi (6,415.69 km) |
| Issum to Strongsville (Ohio) | 4,001.62 mi (6,439.98 km) |
| Issum to Stuart (Florida) | 4,632.28 mi (7,454.94 km) |
| Issum to Stuarts Draft (Virginia) | 4,048.55 mi (6,515.50 km) |
| Issum to Sturgis (Michigan) | 4,113.52 mi (6,620.06 km) |
| Issum to Suamico (Wisconsin) | 4,074.43 mi (6,557.15 km) |
| Issum to Sudley (Virginia) | 3,951.36 mi (6,359.10 km) |
| Issum to Suffern (New York) | 3,711.86 mi (5,973.66 km) |
| Issum to Suffolk (Virginia) | 4,015.72 mi (6,462.68 km) |
