| Issum to Superior (Colorado) | 4,898.80 mi (7,883.85 km) |
| Issum to Superior (Wisconsin) | 4,114.85 mi (6,622.21 km) |
| Issum to Surprise (Arizona) | 5,484.55 mi (8,826.53 km) |
| Issum to Susanville (California) | 5,330.15 mi (8,578.04 km) |
| Issum to Sussex (Wisconsin) | 4,151.98 mi (6,681.97 km) |
| Issum to Suwanee (Georgia) | 4,441.14 mi (7,147.33 km) |
| Issum to Swansea (Illinois) | 4,442.57 mi (7,149.62 km) |
| Issum to Sweetwater (Florida) | 4,710.31 mi (7,580.51 km) |
| Issum to Sweetwater (Texas) | 5,142.64 mi (8,276.28 km) |
| Issum to Sycamore (Illinois) | 4,223.92 mi (6,797.75 km) |
| Issum to Sylacauga (Alabama) | 4,571.45 mi (7,357.04 km) |
| Issum to Sylvania (Ohio) | 4,053.91 mi (6,524.14 km) |
| Issum to Syosset (New York) | 3,699.79 mi (5,954.23 km) |
| Issum to Syracuse (New York) | 3,704.29 mi (5,961.48 km) |
| Issum to Syracuse (Utah) | 5,049.68 mi (8,126.68 km) |
