| Issum to University Place (Washington) | 4,974.93 mi (8,006.38 km) |
| Issum to Upland (California) | 5,619.82 mi (9,044.23 km) |
| Issum to Upper Arlington (Ohio) | 4,109.79 mi (6,614.07 km) |
| Issum to Upper Grand Lagoon (Florida) | 4,704.32 mi (7,570.87 km) |
| Issum to Upper Montclair (New Jersey) | 3,726.32 mi (5,996.93 km) |
| Issum to Urbana (Illinois) | 4,298.63 mi (6,917.98 km) |
| Issum to Urbana (Maryland) | 3,920.10 mi (6,308.79 km) |
| Issum to Urbana (Ohio) | 4,131.95 mi (6,649.74 km) |
| Issum to Urbandale (Iowa) | 4,423.96 mi (7,119.68 km) |
| Issum to Utica (New York) | 3,666.26 mi (5,900.28 km) |
| Issum to Uvalde (Texas) | 5,296.73 mi (8,524.26 km) |
| Issum to Vacaville (California) | 5,489.65 mi (8,834.73 km) |
| Issum to Vadnais Heights (Minnesota) | 4,228.61 mi (6,805.29 km) |
| Issum to Vail (Arizona) | 5,522.74 mi (8,888.00 km) |
| Issum to Valdosta (Georgia) | 4,570.68 mi (7,355.79 km) |
