| Ithaca to Orbetello | 4,249.43 mi (6,838.79 km) |
| Ithaca to Oria | 4,598.72 mi (7,400.93 km) |
| Ithaca to Oristano | 4,230.33 mi (6,808.05 km) |
| Ithaca to Orta Nova | 4,483.82 mi (7,216.01 km) |
| Ithaca to Orte | 4,298.69 mi (6,918.07 km) |
| Ithaca to Ortona | 4,388.14 mi (7,062.03 km) |
| Ithaca to Orvieto | 4,277.16 mi (6,883.43 km) |
| Ithaca to Orzinuovi | 4,087.15 mi (6,577.63 km) |
| Ithaca to Osimo | 4,305.89 mi (6,929.66 km) |
| Ithaca to Ospitaletto | 4,087.45 mi (6,578.12 km) |
| Ithaca to Ostuni | 4,587.00 mi (7,382.07 km) |
| Ithaca to Ottaviano | 4,450.57 mi (7,162.50 km) |
| Ithaca to Ovada | 4,060.08 mi (6,534.07 km) |
| Ithaca to Ozieri | 4,223.05 mi (6,796.35 km) |
| Ithaca to Paceco | 4,480.88 mi (7,211.28 km) |
