| Ithaca to Elyria (Ohio) | 297.33 mi (478.51 km) |
| Ithaca to Emeryville (California) | 2,409.94 mi (3,878.42 km) |
| Ithaca to Emmaus (Pennsylvania) | 141.79 mi (228.19 km) |
| Ithaca to Emporia (Kansas) | 1,069.91 mi (1,721.86 km) |
| Ithaca to Encinitas (California) | 2,295.26 mi (3,693.86 km) |
| Ithaca to Endicott (New York) | 32.81 mi (52.81 km) |
| Ithaca to Endwell (New York) | 33.35 mi (53.67 km) |
| Ithaca to Englewood (Colorado) | 1,490.07 mi (2,398.04 km) |
| Ithaca to Englewood (Florida) | 1,118.73 mi (1,800.43 km) |
| Ithaca to Englewood (New Jersey) | 168.96 mi (271.92 km) |
| Ithaca to Englewood (Ohio) | 443.16 mi (713.20 km) |
| Ithaca to Enid (Oklahoma) | 1,210.26 mi (1,947.73 km) |
| Ithaca to Ennis (Texas) | 1,302.64 mi (2,096.40 km) |
| Ithaca to Ensley (Florida) | 1,016.01 mi (1,635.11 km) |
| Ithaca to Enterprise (Alabama) | 924.17 mi (1,487.31 km) |
