| James Island to Sacile | 4,744.02 mi (7,634.76 km) |
| James Island to Sala Consilina | 5,059.25 mi (8,142.07 km) |
| James Island to Salemi | 5,013.02 mi (8,067.68 km) |
| James Island to Salerno | 5,011.24 mi (8,064.81 km) |
| James Island to Salo | 4,668.86 mi (7,513.80 km) |
| James Island to Salsomaggiore Terme | 4,666.81 mi (7,510.51 km) |
| James Island to Saluzzo | 4,559.73 mi (7,338.18 km) |
| James Island to Salzano | 4,740.23 mi (7,628.66 km) |
| James Island to Samarate | 4,591.10 mi (7,388.67 km) |
| James Island to San Benedetto del Tronto | 4,897.94 mi (7,882.47 km) |
| James Island to San Biagio di Callalta | 4,747.21 mi (7,639.90 km) |
| James Island to San Bonifacio | 4,707.63 mi (7,576.20 km) |
| James Island to San Casciano in Val di Pesa | 4,754.76 mi (7,652.05 km) |
| James Island to San Cataldo | 5,080.88 mi (8,176.89 km) |
| James Island to San Cesareo | 4,884.59 mi (7,860.98 km) |
