| James Island to Sestu | 4,788.03 mi (7,705.58 km) |
| James Island to Settimo Torinese | 4,558.95 mi (7,336.93 km) |
| James Island to Seveso | 4,606.05 mi (7,412.72 km) |
| James Island to Sezze | 4,906.84 mi (7,896.79 km) |
| James Island to Siano | 5,004.22 mi (8,053.52 km) |
| James Island to Siena | 4,771.48 mi (7,678.95 km) |
| James Island to Signa | 4,747.13 mi (7,639.77 km) |
| James Island to Silea | 4,744.47 mi (7,635.49 km) |
| James Island to Silvi Paese | 4,921.20 mi (7,919.90 km) |
| James Island to Sinalunga | 4,792.73 mi (7,713.16 km) |
| James Island to Siniscola | 4,778.36 mi (7,690.03 km) |
| James Island to Sinnai | 4,793.28 mi (7,714.04 km) |
| James Island to Siracusa | 5,157.41 mi (8,300.05 km) |
| James Island to Solaro | 4,604.47 mi (7,410.18 km) |
| James Island to Soliera | 4,711.12 mi (7,581.81 km) |
