| Karlovy Vary to Spilamberto | 403.07 mi (648.68 km) |
| Karlovy Vary to Spilimbergo | 283.46 mi (456.18 km) |
| Karlovy Vary to Spinea | 328.98 mi (529.45 km) |
| Karlovy Vary to Spoleto | 516.49 mi (831.20 km) |
| Karlovy Vary to Spoltore | 540.61 mi (870.03 km) |
| Karlovy Vary to Spresiano | 308.62 mi (496.68 km) |
| Karlovy Vary to Squinzano | 721.68 mi (1,161.44 km) |
| Karlovy Vary to Statte | 699.63 mi (1,125.94 km) |
| Karlovy Vary to Stezzano | 349.69 mi (562.76 km) |
| Karlovy Vary to Strada | 465.09 mi (748.49 km) |
| Karlovy Vary to Stradella | 392.47 mi (631.62 km) |
| Karlovy Vary to Striano | 655.54 mi (1,054.99 km) |
| Karlovy Vary to Subiaco | 573.39 mi (922.78 km) |
| Karlovy Vary to Sulmona | 567.59 mi (913.45 km) |
| Karlovy Vary to Surbo | 725.26 mi (1,167.20 km) |
