| Karlovy Vary to Smolyan | 822.88 mi (1,324.30 km) |
| Karlovy Vary to Sofia | 718.69 mi (1,156.61 km) |
| Karlovy Vary to Sopot | 769.11 mi (1,237.76 km) |
| Karlovy Vary to Sozopol | 887.26 mi (1,427.90 km) |
| Karlovy Vary to Sredets | 871.76 mi (1,402.96 km) |
| Karlovy Vary to Stamboliyski | 788.30 mi (1,268.64 km) |
| Karlovy Vary to Stara Zagora | 811.52 mi (1,306.01 km) |
| Karlovy Vary to Svilengrad | 864.34 mi (1,391.03 km) |
| Karlovy Vary to Svishtov | 743.69 mi (1,196.85 km) |
| Karlovy Vary to Targovishte | 806.68 mi (1,298.23 km) |
| Karlovy Vary to Teteven | 738.92 mi (1,189.18 km) |
| Karlovy Vary to Troyan | 756.23 mi (1,217.04 km) |
| Karlovy Vary to Tryavna | 784.84 mi (1,263.08 km) |
| Karlovy Vary to Tutrakan | 772.47 mi (1,243.18 km) |
| Karlovy Vary to Varna | 859.23 mi (1,382.79 km) |
