| Karlovy Vary to Skarzysko-Kamienna | 357.32 mi (575.06 km) |
| Karlovy Vary to Skawina | 308.82 mi (496.99 km) |
| Karlovy Vary to Skierniewice | 337.60 mi (543.31 km) |
| Karlovy Vary to Skoczow | 264.25 mi (425.27 km) |
| Karlovy Vary to Skwierzyna | 199.02 mi (320.29 km) |
| Karlovy Vary to Slawno | 327.24 mi (526.64 km) |
| Karlovy Vary to Slubice | 163.70 mi (263.46 km) |
| Karlovy Vary to Slupca | 258.87 mi (416.62 km) |
| Karlovy Vary to Slupsk | 341.05 mi (548.87 km) |
| Karlovy Vary to Sochaczew | 347.02 mi (558.47 km) |
| Karlovy Vary to Sokolka | 503.33 mi (810.03 km) |
| Karlovy Vary to Sokolow Podlaski | 431.44 mi (694.33 km) |
| Karlovy Vary to Solec Kujawski | 302.59 mi (486.98 km) |
| Karlovy Vary to Sopot | 377.60 mi (607.69 km) |
| Karlovy Vary to Sosnowiec | 276.51 mi (445.00 km) |
