| Karlovy Vary to Setubal | 1,336.82 mi (2,151.41 km) |
| Karlovy Vary to Sever do Vouga | 1,213.71 mi (1,953.28 km) |
| Karlovy Vary to Silves | 1,385.83 mi (2,230.28 km) |
| Karlovy Vary to Sines | 1,363.50 mi (2,194.34 km) |
| Karlovy Vary to Sintra | 1,343.00 mi (2,161.34 km) |
| Karlovy Vary to Sobrado de Paiva | 1,196.50 mi (1,925.57 km) |
| Karlovy Vary to Sobral de Monte Agraco | 1,323.39 mi (2,129.79 km) |
| Karlovy Vary to Soure | 1,255.06 mi (2,019.82 km) |
| Karlovy Vary to Tabua | 1,216.95 mi (1,958.49 km) |
| Karlovy Vary to Tavira | 1,360.24 mi (2,189.09 km) |
| Karlovy Vary to Tomar | 1,267.23 mi (2,039.41 km) |
| Karlovy Vary to Tondela | 1,212.03 mi (1,950.58 km) |
| Karlovy Vary to Torre de Moncorvo | 1,143.64 mi (1,840.51 km) |
| Karlovy Vary to Torres Novas | 1,278.03 mi (2,056.79 km) |
| Karlovy Vary to Torres Vedras | 1,324.83 mi (2,132.10 km) |
