| Karlovy Vary to Sevnica | 312.45 mi (502.83 km) |
| Karlovy Vary to Sezana | 316.18 mi (508.84 km) |
| Karlovy Vary to Skocjan | 318.89 mi (513.20 km) |
| Karlovy Vary to Skofja Loka | 288.36 mi (464.08 km) |
| Karlovy Vary to Skofljica | 303.76 mi (488.86 km) |
| Karlovy Vary to Slovenj Gradec | 276.31 mi (444.68 km) |
| Karlovy Vary to Slovenska Bistrica | 292.91 mi (471.40 km) |
| Karlovy Vary to Slovenske Konjice | 293.35 mi (472.09 km) |
| Karlovy Vary to Smarje | 302.12 mi (486.21 km) |
| Karlovy Vary to Smarjeske Toplice | 320.69 mi (516.10 km) |
| Karlovy Vary to Smartno | 303.21 mi (487.97 km) |
| Karlovy Vary to Smartno | 287.21 mi (462.22 km) |
| Karlovy Vary to Sodrazica | 319.34 mi (513.93 km) |
| Karlovy Vary to Solcava | 276.20 mi (444.51 km) |
| Karlovy Vary to Sostanj | 284.20 mi (457.38 km) |
