| Karlovy Vary to Olomouc | 199.68 mi (321.35 km) |
| Karlovy Vary to Opava | 223.96 mi (360.42 km) |
| Karlovy Vary to Orlova | 248.01 mi (399.13 km) |
| Karlovy Vary to Ostrava | 242.04 mi (389.52 km) |
| Karlovy Vary to Ostrov | 5.98 mi (9.63 km) |
| Karlovy Vary to Otrokovice | 219.67 mi (353.52 km) |
| Karlovy Vary to Pardubice | 129.40 mi (208.26 km) |
| Karlovy Vary to Pelhrimov | 118.43 mi (190.59 km) |
| Karlovy Vary to Pisek | 85.40 mi (137.43 km) |
| Karlovy Vary to Plzen | 40.22 mi (64.72 km) |
| Karlovy Vary to Podebrady | 99.56 mi (160.23 km) |
| Karlovy Vary to Policka | 154.92 mi (249.32 km) |
| Karlovy Vary to Prachatice | 98.04 mi (157.79 km) |
| Karlovy Vary to Prague | 69.27 mi (111.48 km) |
| Karlovy Vary to Prelouc | 119.76 mi (192.74 km) |
