| Karlovy Vary to Southern Pines (North Carolina) | 4,492.82 mi (7,230.50 km) |
| Karlovy Vary to Southfield (Michigan) | 4,287.53 mi (6,900.11 km) |
| Karlovy Vary to Southgate (Michigan) | 4,298.56 mi (6,917.86 km) |
| Karlovy Vary to Southlake (Texas) | 5,282.06 mi (8,500.66 km) |
| Karlovy Vary to Spanaway (Washington) | 5,203.70 mi (8,374.55 km) |
| Karlovy Vary to Spanish Fork (Utah) | 5,348.45 mi (8,607.49 km) |
| Karlovy Vary to Spanish Lake (Missouri) | 4,723.72 mi (7,602.09 km) |
| Karlovy Vary to Spanish Springs (Nevada) | 5,592.13 mi (8,999.67 km) |
| Karlovy Vary to Sparks (Nevada) | 5,598.37 mi (9,009.71 km) |
| Karlovy Vary to Spartanburg (South Carolina) | 4,604.86 mi (7,410.80 km) |
| Karlovy Vary to Spearfish (South Dakota) | 4,871.55 mi (7,840.01 km) |
| Karlovy Vary to Speedway (Indiana) | 4,528.51 mi (7,287.92 km) |
| Karlovy Vary to Spencer (Iowa) | 4,670.10 mi (7,515.80 km) |
| Karlovy Vary to Spokane (Washington) | 5,055.55 mi (8,136.12 km) |
| Karlovy Vary to Spokane Valley (Washington) | 5,051.10 mi (8,128.96 km) |
