| Karlsdorf-Neuthard to Siegburg | 129.52 mi (208.45 km) |
| Karlsdorf-Neuthard to Siegen | 122.95 mi (197.86 km) |
| Karlsdorf-Neuthard to Sigmaringen | 78.76 mi (126.76 km) |
| Karlsdorf-Neuthard to Simbach am Inn | 212.59 mi (342.13 km) |
| Karlsdorf-Neuthard to Simmerath | 142.17 mi (228.79 km) |
| Karlsdorf-Neuthard to Sindelfingen | 35.90 mi (57.77 km) |
| Karlsdorf-Neuthard to Sinsheim | 17.22 mi (27.71 km) |
| Karlsdorf-Neuthard to Sinzheim | 31.02 mi (49.92 km) |
| Karlsdorf-Neuthard to Sinzig | 113.09 mi (182.00 km) |
| Karlsdorf-Neuthard to Soest | 169.31 mi (272.48 km) |
| Karlsdorf-Neuthard to Solingen | 154.46 mi (248.58 km) |
| Karlsdorf-Neuthard to Soltau | 271.62 mi (437.12 km) |
| Karlsdorf-Neuthard to Sommerda | 180.42 mi (290.35 km) |
| Karlsdorf-Neuthard to Sondershausen | 185.12 mi (297.92 km) |
| Karlsdorf-Neuthard to Sonneberg | 144.02 mi (231.77 km) |
