| Karlsruhe to Seysses | 509.24 mi (819.54 km) |
| Karlsruhe to Sin-le-Noble | 254.27 mi (409.20 km) |
| Karlsruhe to Six-Fours-les-Plages | 426.54 mi (686.45 km) |
| Karlsruhe to Soissons | 230.78 mi (371.41 km) |
| Karlsruhe to Soisy-sous-Montmorency | 276.64 mi (445.21 km) |
| Karlsruhe to Sollies-Pont | 417.64 mi (672.13 km) |
| Karlsruhe to Somain | 247.20 mi (397.84 km) |
| Karlsruhe to Sorgues | 384.07 mi (618.10 km) |
| Karlsruhe to Sotteville-les-Rouen | 331.17 mi (532.96 km) |
| Karlsruhe to Soyaux | 448.96 mi (722.53 km) |
| Karlsruhe to Stains | 272.98 mi (439.33 km) |
| Karlsruhe to Stiring-Wendel | 68.00 mi (109.44 km) |
| Karlsruhe to Strasbourg | 41.99 mi (67.58 km) |
| Karlsruhe to Sucy-en-Brie | 267.63 mi (430.70 km) |
| Karlsruhe to Suresnes | 280.74 mi (451.81 km) |
