| Karlsruhe to Delitzsch | 245.91 mi (395.75 km) |
| Karlsruhe to Delmenhorst | 279.41 mi (449.66 km) |
| Karlsruhe to Demmin | 392.65 mi (631.91 km) |
| Karlsruhe to Denkendorf | 46.84 mi (75.38 km) |
| Karlsruhe to Denzlingen | 69.25 mi (111.45 km) |
| Karlsruhe to Dessau-Rosslau | 257.79 mi (414.87 km) |
| Karlsruhe to Detmold | 203.44 mi (327.41 km) |
| Karlsruhe to Dettingen an der Erms | 54.23 mi (87.28 km) |
| Karlsruhe to Dieburg | 64.73 mi (104.17 km) |
| Karlsruhe to Diedorf | 117.01 mi (188.31 km) |
| Karlsruhe to Dielheim | 24.08 mi (38.76 km) |
| Karlsruhe to Diepholz | 248.60 mi (400.09 km) |
| Karlsruhe to Diessen am Ammersee | 143.52 mi (230.98 km) |
| Karlsruhe to Dietzenbach | 71.66 mi (115.33 km) |
| Karlsruhe to Diez | 95.66 mi (153.96 km) |
