| Karlsruhe to Durmersheim | 7.56 mi (12.17 km) |
| Karlsruhe to Dusseldorf | 169.60 mi (272.95 km) |
| Karlsruhe to Eberbach | 41.01 mi (66.01 km) |
| Karlsruhe to Ebersbach an der Fils | 54.81 mi (88.20 km) |
| Karlsruhe to Ebersberg | 175.05 mi (281.71 km) |
| Karlsruhe to Eberswalde | 354.39 mi (570.34 km) |
| Karlsruhe to Eching | 154.59 mi (248.79 km) |
| Karlsruhe to Eckernforde | 382.52 mi (615.61 km) |
| Karlsruhe to Edemissen | 245.87 mi (395.69 km) |
| Karlsruhe to Edewecht | 285.02 mi (458.69 km) |
| Karlsruhe to Edingen-Neckarhausen | 31.63 mi (50.90 km) |
| Karlsruhe to Efringen-Kirchen | 101.14 mi (162.77 km) |
| Karlsruhe to Egelsbach | 67.38 mi (108.44 km) |
| Karlsruhe to Eggenfelden | 203.13 mi (326.90 km) |
| Karlsruhe to Eggenstein-Leopoldshafen | 4.77 mi (7.67 km) |
