| Karlsruhe to Elmshorn | 332.06 mi (534.40 km) |
| Karlsruhe to Elsdorf | 156.00 mi (251.06 km) |
| Karlsruhe to Elsenfeld | 67.45 mi (108.55 km) |
| Karlsruhe to Elsfleth | 291.87 mi (469.72 km) |
| Karlsruhe to Elze | 222.48 mi (358.05 km) |
| Karlsruhe to Emden | 305.51 mi (491.67 km) |
| Karlsruhe to Emmendingen | 66.38 mi (106.83 km) |
| Karlsruhe to Emsburen | 238.77 mi (384.27 km) |
| Karlsruhe to Emsdetten | 221.88 mi (357.08 km) |
| Karlsruhe to Emstek | 263.30 mi (423.75 km) |
| Karlsruhe to Engelskirchen | 143.27 mi (230.57 km) |
| Karlsruhe to Engen | 81.66 mi (131.41 km) |
| Karlsruhe to Enger | 215.97 mi (347.57 km) |
| Karlsruhe to Eningen unter Achalm | 53.05 mi (85.38 km) |
| Karlsruhe to Enkesen | 173.18 mi (278.70 km) |
