| Karlsruhe to Idar-Oberstein | 69.02 mi (111.08 km) |
| Karlsruhe to Idstein | 83.90 mi (135.03 km) |
| Karlsruhe to Illertissen | 94.25 mi (151.67 km) |
| Karlsruhe to Illingen | 66.09 mi (106.36 km) |
| Karlsruhe to Ilmenau | 161.07 mi (259.21 km) |
| Karlsruhe to Ilsede | 238.17 mi (383.30 km) |
| Karlsruhe to Ilsenburg | 221.43 mi (356.35 km) |
| Karlsruhe to Ilsfeld | 38.43 mi (61.85 km) |
| Karlsruhe to Ilvesheim | 32.85 mi (52.87 km) |
| Karlsruhe to Immenstadt im Allgau | 129.91 mi (209.07 km) |
| Karlsruhe to Ingelheim | 68.51 mi (110.25 km) |
| Karlsruhe to Ingolstadt | 138.29 mi (222.56 km) |
| Karlsruhe to Iserlohn | 167.24 mi (269.15 km) |
| Karlsruhe to Isernhagen-Sud | 245.02 mi (394.32 km) |
| Karlsruhe to Ismaning | 158.77 mi (255.52 km) |
