| Karlsruhe to Schoningen | 243.02 mi (391.10 km) |
| Karlsruhe to Schonwalde-Siedlung | 321.14 mi (516.83 km) |
| Karlsruhe to Schopfheim | 97.71 mi (157.25 km) |
| Karlsruhe to Schorndorf | 53.29 mi (85.75 km) |
| Karlsruhe to Schortens | 313.20 mi (504.04 km) |
| Karlsruhe to Schotten | 107.80 mi (173.49 km) |
| Karlsruhe to Schramberg | 54.06 mi (87.00 km) |
| Karlsruhe to Schriesheim | 34.09 mi (54.86 km) |
| Karlsruhe to Schrobenhausen | 134.43 mi (216.35 km) |
| Karlsruhe to Schuttorf | 234.36 mi (377.16 km) |
| Karlsruhe to Schwabach | 120.26 mi (193.54 km) |
| Karlsruhe to Schwabisch Gmund | 65.03 mi (104.65 km) |
| Karlsruhe to Schwabisch Hall | 60.79 mi (97.83 km) |
| Karlsruhe to Schwabmunchen | 121.78 mi (195.99 km) |
| Karlsruhe to Schwaig | 130.10 mi (209.38 km) |
