| Karlsruhe to Twist | 256.32 mi (412.51 km) |
| Karlsruhe to Twistringen | 262.14 mi (421.87 km) |
| Karlsruhe to Ubach-Palenberg | 166.52 mi (267.99 km) |
| Karlsruhe to Uberherrn | 78.81 mi (126.84 km) |
| Karlsruhe to Uberlingen | 92.68 mi (149.15 km) |
| Karlsruhe to Ubstadt-Weiher | 14.72 mi (23.69 km) |
| Karlsruhe to Ueckermunde | 407.13 mi (655.21 km) |
| Karlsruhe to Uelzen | 288.99 mi (465.08 km) |
| Karlsruhe to Uetersen | 327.78 mi (527.52 km) |
| Karlsruhe to Uetze | 251.46 mi (404.69 km) |
| Karlsruhe to Uhingen | 57.93 mi (93.22 km) |
| Karlsruhe to Ulm | 83.41 mi (134.23 km) |
| Karlsruhe to Unna | 177.33 mi (285.38 km) |
| Karlsruhe to Unterfohring | 158.81 mi (255.58 km) |
| Karlsruhe to Unterhaching | 160.49 mi (258.28 km) |
