| Karlsruhe to Roeselare | 269.98 mi (434.49 km) |
| Karlsruhe to Ronse | 245.32 mi (394.80 km) |
| Karlsruhe to Rotselaar | 211.92 mi (341.05 km) |
| Karlsruhe to Rumst | 227.62 mi (366.32 km) |
| Karlsruhe to Saint-Ghislain | 227.73 mi (366.49 km) |
| Karlsruhe to Saint-Nicolas | 170.18 mi (273.87 km) |
| Karlsruhe to Saint-Vith | 134.41 mi (216.32 km) |
| Karlsruhe to Scherpenheuvel | 205.70 mi (331.04 km) |
| Karlsruhe to Schilde | 229.10 mi (368.70 km) |
| Karlsruhe to Schoten | 232.04 mi (373.44 km) |
| Karlsruhe to Seneffe | 213.14 mi (343.02 km) |
| Karlsruhe to Seraing | 169.10 mi (272.15 km) |
| Karlsruhe to Sint-Amandsberg | 250.20 mi (402.67 km) |
| Karlsruhe to Sint-Andries | 276.38 mi (444.78 km) |
| Karlsruhe to Sint-Genesius-Rode | 216.80 mi (348.91 km) |
