| Karlsruhe to Impruneta | 392.15 mi (631.10 km) |
| Karlsruhe to Induno Olona | 219.20 mi (352.77 km) |
| Karlsruhe to Inverigo | 229.51 mi (369.36 km) |
| Karlsruhe to Inveruno | 242.21 mi (389.80 km) |
| Karlsruhe to Inzago | 245.43 mi (394.98 km) |
| Karlsruhe to Iseo | 244.03 mi (392.74 km) |
| Karlsruhe to Isernia | 584.64 mi (940.88 km) |
| Karlsruhe to Isola Capo Rizzuto | 816.65 mi (1,314.28 km) |
| Karlsruhe to Isola del Liri | 564.90 mi (909.12 km) |
| Karlsruhe to Isola della Scala | 285.94 mi (460.17 km) |
| Karlsruhe to Isola Vicentina | 273.37 mi (439.95 km) |
| Karlsruhe to Ispica | 905.62 mi (1,457.46 km) |
| Karlsruhe to Istrana | 287.58 mi (462.82 km) |
| Karlsruhe to Itri | 589.09 mi (948.05 km) |
| Karlsruhe to Ittiri | 581.07 mi (935.15 km) |
