| Karlsruhe to Matelica | 454.34 mi (731.18 km) |
| Karlsruhe to Matera | 701.59 mi (1,129.10 km) |
| Karlsruhe to Matino | 782.45 mi (1,259.23 km) |
| Karlsruhe to Mazzarino | 859.51 mi (1,383.25 km) |
| Karlsruhe to Meda | 233.69 mi (376.08 km) |
| Karlsruhe to Medesano | 305.38 mi (491.47 km) |
| Karlsruhe to Medicina | 348.00 mi (560.06 km) |
| Karlsruhe to Meldola | 378.69 mi (609.44 km) |
| Karlsruhe to Melegnano | 255.88 mi (411.81 km) |
| Karlsruhe to Melendugno | 775.29 mi (1,247.70 km) |
| Karlsruhe to Melfi | 656.23 mi (1,056.10 km) |
| Karlsruhe to Melilli | 883.63 mi (1,422.06 km) |
| Karlsruhe to Melito di Napoli | 627.12 mi (1,009.25 km) |
| Karlsruhe to Melito di Porto Salvo | 850.10 mi (1,368.10 km) |
| Karlsruhe to Melzo | 247.06 mi (397.61 km) |
