| Karlsruhe to Somma Lombardo | 230.21 mi (370.49 km) |
| Karlsruhe to Somma Vesuviana | 634.42 mi (1,021.00 km) |
| Karlsruhe to Sommacampagna | 274.50 mi (441.76 km) |
| Karlsruhe to Sona | 272.06 mi (437.85 km) |
| Karlsruhe to Sondrio | 207.73 mi (334.31 km) |
| Karlsruhe to Sora | 563.51 mi (906.88 km) |
| Karlsruhe to Sorbolo | 303.35 mi (488.19 km) |
| Karlsruhe to Soresina | 266.11 mi (428.26 km) |
| Karlsruhe to Sorisole | 233.52 mi (375.81 km) |
| Karlsruhe to Sorrento | 648.31 mi (1,043.36 km) |
| Karlsruhe to Sorso | 567.38 mi (913.11 km) |
| Karlsruhe to Sortino | 883.12 mi (1,421.25 km) |
| Karlsruhe to Soverato Marina | 819.73 mi (1,319.23 km) |
| Karlsruhe to Sovicille | 418.08 mi (672.84 km) |
| Karlsruhe to Spello | 463.49 mi (745.91 km) |
