| Karlsruhe to Srem | 433.40 mi (697.49 km) |
| Karlsruhe to Sroda Slaska | 391.39 mi (629.89 km) |
| Karlsruhe to Sroda Wielkopolska | 448.02 mi (721.03 km) |
| Karlsruhe to Stalowa Wola | 617.23 mi (993.34 km) |
| Karlsruhe to Starachowice | 578.65 mi (931.24 km) |
| Karlsruhe to Stargard Szczecinski | 414.58 mi (667.20 km) |
| Karlsruhe to Starogard Gdanski | 553.41 mi (890.62 km) |
| Karlsruhe to Stary Sacz | 552.01 mi (888.37 km) |
| Karlsruhe to Staszow | 578.62 mi (931.21 km) |
| Karlsruhe to Strzegom | 377.42 mi (607.40 km) |
| Karlsruhe to Strzelce Krajenskie | 409.13 mi (658.43 km) |
| Karlsruhe to Strzelce Opolskie | 452.49 mi (728.22 km) |
| Karlsruhe to Strzelin | 404.29 mi (650.65 km) |
| Karlsruhe to Strzyzow | 603.23 mi (970.81 km) |
| Karlsruhe to Sucha Beskidzka | 505.22 mi (813.07 km) |
