| Karlsruhe to Cesky Tesin | 462.28 mi (743.97 km) |
| Karlsruhe to Cheb | 192.56 mi (309.89 km) |
| Karlsruhe to Chocen | 357.29 mi (575.00 km) |
| Karlsruhe to Chodov | 212.04 mi (341.24 km) |
| Karlsruhe to Chomutov | 245.23 mi (394.67 km) |
| Karlsruhe to Chotebor | 330.50 mi (531.88 km) |
| Karlsruhe to Chrudim | 337.99 mi (543.94 km) |
| Karlsruhe to Decin | 285.08 mi (458.80 km) |
| Karlsruhe to Dobris | 264.52 mi (425.71 km) |
| Karlsruhe to Domazlice | 206.24 mi (331.91 km) |
| Karlsruhe to Duchcov | 262.39 mi (422.27 km) |
| Karlsruhe to Dvur Kralove nad Labem | 345.06 mi (555.33 km) |
| Karlsruhe to Frenstat pod Radhostem | 443.29 mi (713.41 km) |
| Karlsruhe to Frydek-Mistek | 449.82 mi (723.91 km) |
| Karlsruhe to Frydlant nad Ostravici | 450.03 mi (724.25 km) |
