| Karlsruhe to Sevnica | 382.74 mi (615.97 km) |
| Karlsruhe to Sezana | 342.83 mi (551.73 km) |
| Karlsruhe to Skocjan | 386.38 mi (621.81 km) |
| Karlsruhe to Skofja Loka | 337.67 mi (543.42 km) |
| Karlsruhe to Skofljica | 355.79 mi (572.59 km) |
| Karlsruhe to Slovenj Gradec | 354.73 mi (570.88 km) |
| Karlsruhe to Slovenska Bistrica | 379.17 mi (610.21 km) |
| Karlsruhe to Slovenske Konjice | 374.89 mi (603.32 km) |
| Karlsruhe to Smarje | 382.79 mi (616.04 km) |
| Karlsruhe to Smarjeske Toplice | 385.51 mi (620.41 km) |
| Karlsruhe to Smartno | 363.56 mi (585.09 km) |
| Karlsruhe to Smartno | 359.52 mi (578.59 km) |
| Karlsruhe to Sodrazica | 367.70 mi (591.75 km) |
| Karlsruhe to Solcava | 342.53 mi (551.25 km) |
| Karlsruhe to Sostanj | 358.25 mi (576.55 km) |
