| Karlsruhe to Olivenza | 1,047.77 mi (1,686.22 km) |
| Karlsruhe to Olot | 551.22 mi (887.10 km) |
| Karlsruhe to Onate | 662.23 mi (1,065.76 km) |
| Karlsruhe to Onda | 756.05 mi (1,216.75 km) |
| Karlsruhe to Onteniente | 833.28 mi (1,341.04 km) |
| Karlsruhe to Orihuela | 886.70 mi (1,427.00 km) |
| Karlsruhe to Osuna | 1,057.76 mi (1,702.30 km) |
| Karlsruhe to Ourense | 907.94 mi (1,461.19 km) |
| Karlsruhe to Oviedo | 783.64 mi (1,261.15 km) |
| Karlsruhe to Paiporta | 791.97 mi (1,274.55 km) |
| Karlsruhe to Pajara | 1,859.13 mi (2,991.98 km) |
| Karlsruhe to Palafolls | 576.31 mi (927.48 km) |
| Karlsruhe to Palafrugell | 551.58 mi (887.68 km) |
| Karlsruhe to Palamos | 556.80 mi (896.08 km) |
| Karlsruhe to Palencia | 789.26 mi (1,270.19 km) |
