| Karlsruhe to Sabinanigo | 615.44 mi (990.45 km) |
| Karlsruhe to Sagunto | 773.25 mi (1,244.42 km) |
| Karlsruhe to Salamanca | 881.61 mi (1,418.82 km) |
| Karlsruhe to Salobrena | 1,039.59 mi (1,673.07 km) |
| Karlsruhe to Salou | 652.17 mi (1,049.57 km) |
| Karlsruhe to Salt | 556.52 mi (895.63 km) |
| Karlsruhe to Salvatierra de Mino | 944.57 mi (1,520.14 km) |
| Karlsruhe to Sama | 779.37 mi (1,254.28 km) |
| Karlsruhe to San Adrian de Besos | 603.53 mi (971.29 km) |
| Karlsruhe to San Agustin de Guadalix | 821.57 mi (1,322.19 km) |
| Karlsruhe to San Andres de la Barca | 608.38 mi (979.10 km) |
| Karlsruhe to San Andres de Llevaneras | 588.46 mi (947.04 km) |
| Karlsruhe to San Andres del Rabanedo | 804.22 mi (1,294.27 km) |
| Karlsruhe to San Bartolome | 1,933.78 mi (3,112.12 km) |
| Karlsruhe to San Baudilio de Llobregat | 612.99 mi (986.51 km) |
