| Karlsruhe to Uhersky Brod | 418.59 mi (673.65 km) |
| Karlsruhe to Unicov | 395.34 mi (636.24 km) |
| Karlsruhe to Usti nad Labem | 275.78 mi (443.83 km) |
| Karlsruhe to Usti nad Orlici | 364.54 mi (586.66 km) |
| Karlsruhe to Valasske Mezirici | 432.47 mi (695.99 km) |
| Karlsruhe to Varnsdorf | 305.77 mi (492.09 km) |
| Karlsruhe to Velke Mezirici | 344.30 mi (554.10 km) |
| Karlsruhe to Veseli nad Moravou | 406.65 mi (654.44 km) |
| Karlsruhe to Vlasim | 296.13 mi (476.58 km) |
| Karlsruhe to Vrchlabi | 339.95 mi (547.09 km) |
| Karlsruhe to Vsetin | 433.59 mi (697.80 km) |
| Karlsruhe to Vyskov | 388.71 mi (625.57 km) |
| Karlsruhe to Vysoke Myto | 354.13 mi (569.91 km) |
| Karlsruhe to Zabreh | 384.95 mi (619.52 km) |
| Karlsruhe to Zatec | 247.25 mi (397.91 km) |
