| Karlsruhe to Duragan | 1,389.97 mi (2,236.94 km) |
| Karlsruhe to Duzce | 1,241.37 mi (1,997.80 km) |
| Karlsruhe to Eceabat | 1,068.99 mi (1,720.37 km) |
| Karlsruhe to Edirne | 1,012.95 mi (1,630.19 km) |
| Karlsruhe to Edremit | 1,122.38 mi (1,806.29 km) |
| Karlsruhe to Elazig | 1,678.38 mi (2,701.10 km) |
| Karlsruhe to Elbistan | 1,608.63 mi (2,588.84 km) |
| Karlsruhe to Eleskirt | 1,789.02 mi (2,879.15 km) |
| Karlsruhe to Emet | 1,224.91 mi (1,971.31 km) |
| Karlsruhe to Emirdag | 1,316.70 mi (2,119.03 km) |
| Karlsruhe to Emirgazi | 1,478.02 mi (2,378.64 km) |
| Karlsruhe to Enez | 1,032.88 mi (1,662.26 km) |
| Karlsruhe to Erbaa | 1,484.45 mi (2,388.99 km) |
| Karlsruhe to Ercis | 1,848.49 mi (2,974.85 km) |
| Karlsruhe to Eregli | 1,503.99 mi (2,420.44 km) |
