| Phoenix (Arizona) to South San Francisco | 644.64 mi (1,037.46 km) |
| Seattle (Washington) to South San Francisco | 688.69 mi (1,108.34 km) |
| Denver (Colorado) to South San Francisco | 955.46 mi (1,537.67 km) |
| San Francisco (California) to South San Francisco | 7.18 mi (11.56 km) |
| Dallas (Texas) to South San Francisco | 1,481.32 mi (2,383.96 km) |
| Minneapolis (Minnesota) to South San Francisco | 1,584.98 mi (2,550.78 km) |
| Houston (Texas) to South San Francisco | 1,638.86 mi (2,637.49 km) |
| St. Louis (Missouri) to South San Francisco | 1,740.65 mi (2,801.31 km) |
| Chicago (Illinois) to South San Francisco | 1,854.81 mi (2,985.02 km) |
| Detroit (Michigan) to South San Francisco | 2,087.01 mi (3,358.72 km) |
| Atlanta (Georgia) to South San Francisco | 2,134.07 mi (3,434.46 km) |
| Tampa (Florida) to South San Francisco | 2,395.30 mi (3,854.86 km) |
| Washington (District of Columbia) to South San Francisco | 2,438.35 mi (3,924.15 km) |
| Baltimore (Maryland) to South San Francisco | 2,453.44 mi (3,948.44 km) |
| Philadelphia (Pennsylvania) to South San Francisco | 2,520.31 mi (4,056.05 km) |
| Brooklyn (New York) to South San Francisco | 2,572.35 mi (4,139.80 km) |
| New York (New York) to South San Francisco | 2,573.01 mi (4,140.85 km) |
| Queens (New York) to South San Francisco | 2,578.77 mi (4,150.13 km) |
| Miami (Florida) to South San Francisco | 2,588.36 mi (4,165.56 km) |
| Boston (Massachusetts) to South San Francisco | 2,695.38 mi (4,337.79 km) |
| Los Angeles (California) to South San Francisco | 332.00 mi (534.31 km) |
| Riverside (California) to South San Francisco | 380.94 mi (613.07 km) |
| Las Vegas (Nevada) to South San Francisco | 406.96 mi (654.93 km) |
| San Diego (California) to South San Francisco | 447.47 mi (720.13 km) |
| Portland (Oregon) to South San Francisco | 544.81 mi (876.79 km) |
