| Key Largo to Santa Venerina | 5,460.48 mi (8,787.79 km) |
| Key Largo to Santeramo in Colle | 5,454.52 mi (8,778.21 km) |
| Key Largo to Santo Stefano di Magra | 5,045.03 mi (8,119.20 km) |
| Key Largo to Santo Stino di Livenza | 5,136.52 mi (8,266.43 km) |
| Key Largo to Sarezzo | 5,025.34 mi (8,087.50 km) |
| Key Largo to Sarno | 5,350.66 mi (8,611.06 km) |
| Key Largo to Saronno | 4,972.49 mi (8,002.44 km) |
| Key Largo to Sarzana | 5,048.23 mi (8,124.34 km) |
| Key Largo to Sassari | 5,056.44 mi (8,137.55 km) |
| Key Largo to Sasso Marconi | 5,102.01 mi (8,210.89 km) |
| Key Largo to Sassuolo | 5,076.93 mi (8,170.53 km) |
| Key Largo to Sava | 5,504.10 mi (8,857.99 km) |
| Key Largo to Saviano | 5,343.19 mi (8,599.04 km) |
| Key Largo to Savigliano | 4,927.51 mi (7,930.06 km) |
| Key Largo to Savignano sul Panaro | 5,090.01 mi (8,191.58 km) |
