| Key Largo to Savignano sul Rubicone | 5,162.55 mi (8,308.33 km) |
| Key Largo to Savona | 4,974.48 mi (8,005.65 km) |
| Key Largo to Scafati | 5,347.91 mi (8,606.62 km) |
| Key Largo to Scalea | 5,434.99 mi (8,746.76 km) |
| Key Largo to Scandiano | 5,071.46 mi (8,161.72 km) |
| Key Largo to Scandicci | 5,114.16 mi (8,230.45 km) |
| Key Largo to Schio | 5,076.74 mi (8,170.23 km) |
| Key Largo to Sciacca | 5,361.99 mi (8,629.29 km) |
| Key Largo to Scicli | 5,463.13 mi (8,792.05 km) |
| Key Largo to Scordia | 5,456.70 mi (8,781.71 km) |
| Key Largo to Scorze | 5,114.25 mi (8,230.60 km) |
| Key Largo to Sedico | 5,101.15 mi (8,209.51 km) |
| Key Largo to Sedriano | 4,972.25 mi (8,002.06 km) |
| Key Largo to Segni | 5,251.21 mi (8,451.00 km) |
| Key Largo to Segrate | 4,987.26 mi (8,026.21 km) |
