| Key Largo to Sesena | 4,447.19 mi (7,157.06 km) |
| Key Largo to Sestao | 4,437.39 mi (7,141.28 km) |
| Key Largo to Sevilla | 4,368.41 mi (7,030.28 km) |
| Key Largo to Sevilla La Nueva | 4,426.62 mi (7,123.95 km) |
| Key Largo to Silla | 4,628.98 mi (7,449.62 km) |
| Key Largo to Silleda | 4,184.08 mi (6,733.63 km) |
| Key Largo to Sitges | 4,709.24 mi (7,578.79 km) |
| Key Largo to Socuellamos | 4,506.34 mi (7,252.25 km) |
| Key Largo to Soller | 4,781.56 mi (7,695.18 km) |
| Key Largo to Solsona | 4,681.63 mi (7,534.36 km) |
| Key Largo to Son Servera | 4,818.07 mi (7,753.93 km) |
| Key Largo to Sonseca | 4,440.05 mi (7,145.57 km) |
| Key Largo to Sopelana | 4,437.75 mi (7,141.87 km) |
| Key Largo to Soria | 4,485.77 mi (7,219.15 km) |
| Key Largo to Suances | 4,384.27 mi (7,055.81 km) |
