| Key Largo to Abilene (Texas) | 1,272.63 mi (2,048.10 km) |
| Key Largo to Accokeek (Maryland) | 957.27 mi (1,540.58 km) |
| Key Largo to Acworth (Georgia) | 668.04 mi (1,075.11 km) |
| Key Largo to Ada (Oklahoma) | 1,176.92 mi (1,894.07 km) |
| Key Largo to Addison (Illinois) | 1,239.75 mi (1,995.18 km) |
| Key Largo to Addison (Texas) | 1,128.21 mi (1,815.68 km) |
| Key Largo to Adelanto (California) | 2,298.83 mi (3,699.60 km) |
| Key Largo to Adelphi (Maryland) | 979.75 mi (1,576.76 km) |
| Key Largo to Adrian (Michigan) | 1,177.61 mi (1,895.18 km) |
| Key Largo to Affton (Missouri) | 1,093.53 mi (1,759.87 km) |
| Key Largo to Agoura Hills (California) | 2,370.93 mi (3,815.64 km) |
| Key Largo to Aguadilla (Puerto Rico) | 967.09 mi (1,556.38 km) |
| Key Largo to Aiken (South Carolina) | 586.29 mi (943.54 km) |
| Key Largo to Akron (Ohio) | 1,104.39 mi (1,777.35 km) |
| Key Largo to Alabaster (Alabama) | 679.75 mi (1,093.96 km) |
