| Key Largo to Cullman (Alabama) | 734.71 mi (1,182.40 km) |
| Key Largo to Culpeper (Virginia) | 932.96 mi (1,501.46 km) |
| Key Largo to Culver City (California) | 2,349.32 mi (3,780.87 km) |
| Key Largo to Cumberland (Maryland) | 1,008.43 mi (1,622.92 km) |
| Key Largo to Cupertino (California) | 2,576.70 mi (4,146.80 km) |
| Key Largo to Cutler Bay (Florida) | 31.74 mi (51.07 km) |
| Key Largo to Cutlerville (Michigan) | 1,260.07 mi (2,027.88 km) |
| Key Largo to Cuyahoga Falls (Ohio) | 1,110.20 mi (1,786.70 km) |
| Key Largo to Cypress (California) | 2,327.76 mi (3,746.17 km) |
| Key Largo to Cypress Gardens (Florida) | 214.06 mi (344.50 km) |
| Key Largo to Cypress Lake (Florida) | 134.70 mi (216.78 km) |
| Key Largo to D'Iberville (Mississippi) | 636.64 mi (1,024.57 km) |
| Key Largo to Dakota Ridge (Colorado) | 1,746.62 mi (2,810.91 km) |
| Key Largo to Dale City (Virginia) | 951.46 mi (1,531.23 km) |
| Key Largo to Dallas (Georgia) | 663.12 mi (1,067.19 km) |
