| Key Largo to Dixon (California) | 2,575.19 mi (4,144.36 km) |
| Key Largo to Dixon (Illinois) | 1,266.17 mi (2,037.70 km) |
| Key Largo to Dobbs Ferry (New York) | 1,160.50 mi (1,867.65 km) |
| Key Largo to Doctor Phillips (Florida) | 239.18 mi (384.93 km) |
| Key Largo to Dodge City (Kansas) | 1,443.34 mi (2,322.83 km) |
| Key Largo to Dolton (Illinois) | 1,212.32 mi (1,951.04 km) |
| Key Largo to Donna (Texas) | 1,100.52 mi (1,771.11 km) |
| Key Largo to Dorado (Puerto Rico) | 1,016.09 mi (1,635.24 km) |
| Key Largo to Doral (Florida) | 47.99 mi (77.24 km) |
| Key Largo to Doraville (Georgia) | 649.65 mi (1,045.52 km) |
| Key Largo to Dothan (Alabama) | 520.25 mi (837.26 km) |
| Key Largo to Douglas (Arizona) | 1,818.74 mi (2,926.98 km) |
| Key Largo to Douglas (Georgia) | 465.40 mi (748.99 km) |
| Key Largo to Douglasville (Georgia) | 648.76 mi (1,044.08 km) |
| Key Largo to Dover (Delaware) | 1,010.86 mi (1,626.82 km) |
