| Key Largo to Eagan (Minnesota) | 1,536.06 mi (2,472.05 km) |
| Key Largo to Eagle (Idaho) | 2,391.77 mi (3,849.18 km) |
| Key Largo to Eagle Mountain (Utah) | 2,099.02 mi (3,378.04 km) |
| Key Largo to Eagle Pass (Texas) | 1,259.59 mi (2,027.11 km) |
| Key Largo to Easley (South Carolina) | 682.38 mi (1,098.18 km) |
| Key Largo to East Bakersfield (California) | 2,391.34 mi (3,848.49 km) |
| Key Largo to East Bethel (Minnesota) | 1,568.79 mi (2,524.73 km) |
| Key Largo to East Chicago (Indiana) | 1,210.75 mi (1,948.52 km) |
| Key Largo to East Cleveland (Ohio) | 1,135.74 mi (1,827.80 km) |
| Key Largo to East Glenville (New York) | 1,279.92 mi (2,059.82 km) |
| Key Largo to East Grand Rapids (Michigan) | 1,266.28 mi (2,037.88 km) |
| Key Largo to East Hemet (California) | 2,264.44 mi (3,644.26 km) |
| Key Largo to East Highland Park (Virginia) | 878.70 mi (1,414.13 km) |
| Key Largo to East Honolulu (Hawaii) | 4,847.03 mi (7,800.54 km) |
| Key Largo to East Islip (New York) | 1,155.56 mi (1,859.70 km) |
