| Key Largo to Hutchinson (Kansas) | 1,359.50 mi (2,187.90 km) |
| Key Largo to Hutchinson (Minnesota) | 1,572.51 mi (2,530.71 km) |
| Key Largo to Hutto (Texas) | 1,110.21 mi (1,786.71 km) |
| Key Largo to Hyattsville (Maryland) | 977.15 mi (1,572.58 km) |
| Key Largo to Hybla Valley (Virginia) | 961.29 mi (1,547.05 km) |
| Key Largo to Idaho Falls (Idaho) | 2,184.87 mi (3,516.22 km) |
| Key Largo to Idylwood (Virginia) | 969.40 mi (1,560.10 km) |
| Key Largo to Ilchester (Maryland) | 996.75 mi (1,604.11 km) |
| Key Largo to Immokalee (Florida) | 109.90 mi (176.86 km) |
| Key Largo to Imperial (California) | 2,180.16 mi (3,508.62 km) |
| Key Largo to Imperial Beach (California) | 2,268.44 mi (3,650.70 km) |
| Key Largo to Independence (Kentucky) | 985.39 mi (1,585.84 km) |
| Key Largo to Independence (Missouri) | 1,260.27 mi (2,028.22 km) |
| Key Largo to Indian Trail (North Carolina) | 687.45 mi (1,106.34 km) |
| Key Largo to Indiana (Pennsylvania) | 1,073.36 mi (1,727.41 km) |
