| Key Largo to Lewiston (Maine) | 1,431.53 mi (2,303.82 km) |
| Key Largo to Lewisville (North Carolina) | 758.69 mi (1,220.99 km) |
| Key Largo to Lewisville (Texas) | 1,138.38 mi (1,832.05 km) |
| Key Largo to Lexington (Kentucky) | 923.63 mi (1,486.43 km) |
| Key Largo to Lexington (Nebraska) | 1,550.91 mi (2,495.95 km) |
| Key Largo to Lexington (North Carolina) | 737.92 mi (1,187.57 km) |
| Key Largo to Lexington (South Carolina) | 614.54 mi (989.00 km) |
| Key Largo to Lexington Park (Maryland) | 936.48 mi (1,507.13 km) |
| Key Largo to Liberal (Kansas) | 1,461.96 mi (2,352.80 km) |
| Key Largo to Liberty (Missouri) | 1,270.40 mi (2,044.52 km) |
| Key Largo to Liberty Lake (Washington) | 2,529.17 mi (4,070.31 km) |
| Key Largo to Liberty Triangle (Florida) | 294.90 mi (474.60 km) |
| Key Largo to Libertyville (Illinois) | 1,261.62 mi (2,030.38 km) |
| Key Largo to Lighthouse Point (Florida) | 82.37 mi (132.56 km) |
| Key Largo to Lilburn (Georgia) | 645.68 mi (1,039.13 km) |
