| Key Largo to Mauldin (South Carolina) | 676.91 mi (1,089.38 km) |
| Key Largo to Maumee (Ohio) | 1,151.54 mi (1,853.23 km) |
| Key Largo to Maumelle (Arkansas) | 981.67 mi (1,579.84 km) |
| Key Largo to Mayagüez (Puerto Rico) | 976.40 mi (1,571.36 km) |
| Key Largo to Mayfield Heights (Ohio) | 1,134.35 mi (1,825.57 km) |
| Key Largo to Mays Chapel (Maryland) | 1,012.69 mi (1,629.76 km) |
| Key Largo to Maywood (California) | 2,337.29 mi (3,761.50 km) |
| Key Largo to Maywood (Illinois) | 1,233.21 mi (1,984.66 km) |
| Key Largo to McAlester (Oklahoma) | 1,139.23 mi (1,833.42 km) |
| Key Largo to McAllen (Texas) | 1,112.34 mi (1,790.14 km) |
| Key Largo to McCalla (Alabama) | 691.48 mi (1,112.84 km) |
| Key Largo to McComb (Mississippi) | 743.88 mi (1,197.17 km) |
| Key Largo to McDonough (Georgia) | 617.11 mi (993.15 km) |
| Key Largo to McFarland (California) | 2,408.58 mi (3,876.24 km) |
| Key Largo to McHenry (Illinois) | 1,271.36 mi (2,046.05 km) |
